A psychological therapy that retrains the brain to reduce or eliminate chronic pain by addressing neuroplastic pain mechanisms. The NIH-funded trial (JAMA Psychiatry, 2021) found that 66% of chronic back pain patients were pain-free or nearly pain-free after PRT, with effects largely maintained at one-year follow-up. PRT focuses on reappraising pain as non-threatening, reducing fear, and breaking pain cycles.
